CD8A Mouse Monoclonal Antibody [Clone ID: CC63]

Specifications

Product Data
Clone Name	CC63
Applications	FC
Recommended Dilution	Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl.
Reactivities	Bovine, Goat, Sheep
Host	Mouse
Isotype	IgG2a
Clonality	Monoclonal
Specificity	This antibody reacts with the CD8 antigen expressed by a subset of T lymphocytes. The antibody precipitates molecules of 34kD and 38kD under reducing conditions.
Formulation	Phosphate buffered saline 0.09% Sodium Azide, 1% Bovine Serum Albumin Label: PE State: Lyophilized Ig fraction Label: R. Phycoerythrin (RPE)
Reconstitution Method	Reconstitute with 1 ml distilled water.
Purification	Affinity chromatography on Protein G
Conjugation	PE
Storage	Prior and following reconstitution store undiluted at 2-8°C. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Stability	Shelf life: One year from despatch.
Database Link	Entrez Gene 281060 Bovine UniProt ID P31783
Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms	CD8 alpha chain, CD8A, MAL
Reference Data