beta 2 Microglobulin (B2M) (NM_004048) Human Recombinant Protein

CAT#: TP720425

Recombinant protein of human beta-2-microglobulin (B2M)

Size: 10 ug 50 ug 500 ug


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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Tag C-6His
Predicted MW 12.8 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Store at -80°C.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_004039
Locus ID 567
UniProt ID P61769
Cytogenetics 15q21.1
Synonyms IMD43
Summary This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Antigen processing and presentation

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