General Info
Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-PDHB (260-359) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: | Monoclonal |
Clone ID: | S3MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000IHC-P 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | PDHB |
Gene ID: | 5162 |
Uniprot ID: | ODPB_HUMAN |
Immunogen Region: | 260-359 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 260-359 of human Pyruvate Dehydrogenase E1 beta subunit (P11177). |
Immunogen Sequence: | GVECEVINMRTIRPMDMETI EASVMKTNHLVTVEGGWPQF GVGAEICARIMEGPAFNFLD APAVRVTGADVPMPYAKILE DNSIPQVKDIIFAIKKTLNI |
Description
Function | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. |
Protein Name | Pyruvate Dehydrogenase E1 Component Subunit Beta - MitochondrialPdhe1-B |
Database Links | Reactome: R-HSA-204174Reactome: R-HSA-389661Reactome: R-HSA-5362517Reactome: R-HSA-70268 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-Pyruvate Dehydrogenase E1 Component Subunit Beta - Mitochondrial antibodyAnti-Pdhe1-B antibodyAnti-PDHB antibodyAnti-PHE1B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance