Anti-Human CD3 - PerCP/Cy5.5
Cat# C2134-25
Size : 25tests
Brand : Leinco Technologies
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AntiHuman CD3 – PerCP/Cy5.5
AntiHuman CD3 – PerCP/Cy5.5
Product No.: C2134
Clone UCHT1 Target CD3 Formats AvailableView All Product Type Monoclonal Antibody Isotype IgG1 Applications FC |
Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Product Concentration 0.1 mg/ml Formulation This PerCp/Cy5.5 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This PerCp/Cy5.5 conjugate is stable when stored at 28°C. Do not freeze. Country of Origin USA Shipping Next Day 28°C RRIDAB_2829216 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for this UCHT1 antibody for staining cells in flow cytometry is ≤ .25 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Clone UCHT1 recognizes an epitope on human CD3ε. Background CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane Tcell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent Tlymphocytes in peripheral blood, and signal transduction during antigen recognition. Antigen Distribution CD3 is expressed on human peripheral blood lymphocytes, splenic lymphocytes, and the majority of TCLL and TALL cells. Ligand/Receptor Peptide antigen bound to MHC NCBI Gene Bank ID UniProt.org Research Area Immunology References & Citations1. van Dongen, J. et al. (1988) Blood 71:603 2. Meuer, SC. et al. (1983) Nature 303:808 3. Beverly, P. et al. (1981) Eur. J. Immunol. 11:329 4. Leukocyte Typing III: Code No. 126, 208 and 471; 4th Workshop: Paper No. T3.2 |