Background

The CD3 T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with the T-cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes. The TCR, ζ-chain, and CD3 molecules together comprise the TCR complex.

Specifications

Clone - MM1A

Isotype - IgG1

Host - Mouse

Known Reactivity - Bison, Bovine, Water Buffalo

Purification - Anti-bovine CD3 monoclonal antibody, clone MM1A, was produced in ascites fluid, clarified by filtration through a 0.2 micrometer filter.

Application

Flow Cytometry - Flow cytometric profile obtained with bovine leukocytes.