7-Methyl-6-thioguanosine [55727-10-1]
Cat# HY-D0995-5mg
Size : 5mg
Brand : MedChemExpress
7-Methyl-6-thioguanosine (MESG) is a chromophoric substrate which can be used for the quantitation of inorganic phosphate. 7-Methyl-6-thioguanosine is also used to determine the activity of purine nucleoside phosphorylase.
For research use only. We do not sell to patients.
7-Methyl-6-thioguanosine Chemical Structure
CAS No. : 55727-10-1
This product is a controlled substance and not for sale in your territory.
Based on 2 publication(s) in Google Scholar
Description |
7-Methyl-6-thioguanosine (MESG) is a chromophoric substrate which can be used for the quantitation of inorganic phosphate. 7-Methyl-6-thioguanosine is also used to determine the activity of purine nucleoside phosphorylase[1][2]. |
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Clinical Trial |
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Molecular Weight |
313.33 |
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Formula |
C11H15N5O4S |
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CAS No. |
55727-10-1 |
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Appearance |
Solid |
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Color |
White to yellow |
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SMILES |
S=C1NC(N)=NC2=C1[N+](C)=CN2[C@H]3[C@@H]([C@@H]([C@@H](CO)O3)O)[O-] |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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Solvent & Solubility |
In Vitro:
DMSO : ≥ 250 mg/mL (797.88 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) H2O : ≥ 125 mg/mL (398.94 mM) *"≥" means soluble, but saturation unknown. Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Purity & Documentation |
Purity: ≥99.0% |
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References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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H2O / DMSO | 1 mM | 3.1915 mL | 15.9576 mL | 31.9152 mL | 79.7881 mL |
5 mM | 0.6383 mL | 3.1915 mL | 6.3830 mL | 15.9576 mL | |
10 mM | 0.3192 mL | 1.5958 mL | 3.1915 mL | 7.9788 mL | |
15 mM | 0.2128 mL | 1.0638 mL | 2.1277 mL | 5.3192 mL | |
20 mM | 0.1596 mL | 0.7979 mL | 1.5958 mL | 3.9894 mL | |
25 mM | 0.1277 mL | 0.6383 mL | 1.2766 mL | 3.1915 mL | |
30 mM | 0.1064 mL | 0.5319 mL | 1.0638 mL | 2.6596 mL | |
40 mM | 0.0798 mL | 0.3989 mL | 0.7979 mL | 1.9947 mL | |
50 mM | 0.0638 mL | 0.3192 mL | 0.6383 mL | 1.5958 mL | |
60 mM | 0.0532 mL | 0.2660 mL | 0.5319 mL | 1.3298 mL | |
80 mM | 0.0399 mL | 0.1995 mL | 0.3989 mL | 0.9974 mL | |
100 mM | 0.0319 mL | 0.1596 mL | 0.3192 mL | 0.7979 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
7-Methyl-6-thioguanosine Related Classifications
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
7-Methyl-6-thioguanosine55727-10-1MESGFluorescent DyeInhibitorinhibitorinhibit