Powder: -20°C for 3 years | In solvent: -80°C for 1 year
3-Oxocholic acid [2304-89-4]
Cat# T19124-500mg
Size : 500mg
Brand : TargetMol
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3-Oxocholic acid
Catalog No. T19124 CAS 2304-89-4
Synonyms: 3-Ketocholic acid
3-Oxocholic acid(3-Ketocholic acid) is the metabolite of bile acid and the main product of bile degradation by Clostridium perfringens in the intestine.3-Oxocholic acid is a steroid acid mainly found in the bile of mammals.
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3-Oxocholic acid, CAS 2304-89-4
| Description | 3-Oxocholic acid(3-Ketocholic acid) is the metabolite of bile acid and the main product of bile degradation by Clostridium perfringens in the intestine.3-Oxocholic acid is a steroid acid mainly found in the bile of mammals. |
| In vivo | Male Goto-Kakizaki (GK) rats are subjected to Ileal Transposition (IT) surgery. In the metabolomics analysis, 3-Oxocholic acid in IT rats is increased compared with Sham-IT rats [1] |
| Synonyms | 3-Ketocholic acid |
| Molecular Weight | 406.56 |
| Formula | C24H38O5 |
| CAS No. | 2304-89-4 |
Storage
Solubility Information
DMSO: 90 mg/mL (221.37 mM), Sonication is recommended.
References and Literature
1. Yan K, et al. The Changes of Serum Metabolites in Diabetic GK Rats after Ileal Transposition Surgery. Obes Surg. 2019 Mar;29(3):882-890. 2. Macdonald I, et al. Identification of 7alpha-, 12alpha-dihydroxy-3-oxo cholanoic acid as the major degradation product from cholic by C. perfringens. J Steroid Biochem. 1978 Apr;9(4):353-8. 3. Wahlström A, et al. Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism. Cell Metab. 2016 Jul 12;24(1):41-50.
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Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Keywords
3-Oxocholic acid 2304-89-4 Metabolism Endogenous Metabolite 3-Oxocholic acid 3-Ketocholic acid inhibitor inhibit