Plxna1 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN313500RB
Plxna1 - mouse gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
Product Images
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
| Donor DNA | RFP-BSD |
| Symbol | Plxna1 |
| Locus ID | 18844 |
| Components | KN313500G1, Plxna1 gRNA vector 1 in pCas-Guide CRISPR vector KN313500G2, Plxna1 gRNA vector 2 in pCas-Guide CRISPR vector KN313500RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_008881 |
| UniProt ID | P70206 |
| Synonyms | 2600013D04Rik; mKIAA4053; NOV; PlexA1; Plxn1 |
| Summary | Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| KN313500 | Plxna1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN313500BN | Plxna1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN313500LP | Plxna1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN513500 | Plxna1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 657,00 EUR | |
| GA203299 | Plxna1 CRISPRa kit - CRISPR gene activation of mouse plexin A1 | 1 657,00 EUR |