Mmp3 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN310182RB
Mmp3 - mouse gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro Luciferase-Puro mBFP-Neo
HDR-mediated knockout kit validation
Product Images
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
| Donor DNA | RFP-BSD |
| Symbol | Mmp3 |
| Locus ID | 17392 |
| Components | KN310182G1, Mmp3 gRNA vector 1 in pCas-Guide CRISPR vector KN310182G2, Mmp3 gRNA vector 2 in pCas-Guide CRISPR vector KN310182RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_010809 |
| UniProt ID | P28862 |
| Synonyms | EMS-2; MMP-3; SL-1; SLN-1; SLN1; Stmy1; STR-1; Str1 |
| Summary | This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded protein is activated by the removal of an N-temrinal activation peptide to generate a zinc-dependent endopeptidase with a broad range of substrates such as proteoglycans, laminin, fibronectin, elastin, and collagens. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. [provided by RefSeq, Feb 2016] |
Documents
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Resources
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| KN310182 | Mmp3 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN310182BN | Mmp3 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN310182LP | Mmp3 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN510182 | Mmp3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 657,00 EUR | |
| GA202683 | Mmp3 CRISPRa kit - CRISPR gene activation of mouse matrix metallopeptidase 3 | 1 657,00 EUR |