Inhbb Mouse Gene Knockout Kit (CRISPR)
CAT#: KN308333
Inhbb - mouse gene knockout kit via CRISPR, HDR mediated
Functional Cassette: Luciferase-Puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
Product Images
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
| Donor DNA | GFP-puro |
| Symbol | Inhbb |
| Locus ID | 16324 |
| Components | KN308333G1, Inhbb gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: CAGGACACCTGTACGTCGTG KN308333G2, Inhbb gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: GGTGGACGGTGACTTCCTGG KN308333D, donor DNA containing left and right homologous arms and GFP-puro functional cassette. Homologous arm and GFP-puro sequences: pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet GCCCATCACC GCCGCTGCCT CGGGCGGCCG TGTCCTCGCT GCGAGCAGCG ACAGGGCGAG GCGCTCAGGT GCGGTCGCGG GGCCCCAGCC GCAGCGCCCT CCGCAGCGCC GCGCCCGGGG TCTCCGGCAC CTTCGCTTCA GTCTCCAGAG CGACTTGCGC CCGCTGCCGC CTCTTCCCTC CACCTTTCCA GCCCGGCCGA GCCAAGCCAC CGTGCCAGCA CCGCTGCTGC CGCTCCTCGC TTTCGCTTCA CCCCGATCAG GGGGCTGCGG TGGCCCTCGA CGCGGAGAGG ATGGGCAGGC TGCAGATGCC TAGGCGCCCC GAGTCGTCAG CGCGCCACTG ACCCGGCGGT CCCCCCCACC CCCTCACCGC CAGCCCGCGT TCCCTTCTGG TCCCCGCGGC GCCCCTTCTC GGCCGCGCGG GAACCCCCGC GGCCCGGCCG GCCCCCTCCC CCTGCGAGCC GGCGGCGGCG CTCCCGGCAG GCGGGCGGGC GGAGGCCCGG GCGGGGGCGG GGCGGGGCGG TGCGCCCAGA GCCCGGAGCC CGGCCCTGAG CTCGCTTCGC CTCGCCTCGC GGCGGGCGCC CTCGTCGCCA GCGGCGCACC GGCCCAACAT CACGCACGCT GTCCCCAAGG CCGCCATGGT CACGGCCCTG CGCAAGCTGC ACGCCGGCAA GGTGCGCGAG GACGGCCGCG TGGAGATCCC GCACCTCGAC GGCCACGCCA GCCCGGGCGC CGACGGCCAG GAGCGCGTCT CCGAGATCAT CAGCTTTGCA GAGACAGGTG GGTTCGGCCA CAGGGAAGCC AGAGGCGGCC GCGATCCCTC CCTTTTTCCT TCTCCTAGGA AGCCCTGCTG CCTTCACCGC CTCTGCAGCC CGCACGCCCC GAGGGCATTT AGGCTCCGGG CAGAGACGTT CTGCGGTGGC CTTGCGCGCT TCCCAGGGTG GCAGTCCTTT TCTATACTGC GCGCCCAGAC TACAGATCCT TTGCGGCTTC CCTTTCCCTG CAGCAACTGG GAAGCACCCT GCCCTTCATC CTGGCTCACG GGAATTGGGC CCCAGCGCCT CTGGGCGCGC GTCCCCCTCC CGGCAGATGC GCGCAGCCCT GGCTCTGCGG GCACTTGCTT AGTGATTGCT TAATGTTTTT GTTTCCCACG ATCCGAGTGT AGGCTTAGCA GTGTAGAGAT GGAGATGTGT GTGCTTGTTGGE100003, scramble sequence in pCas-Guide vector |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_008381 |
| UniProt ID | Q04999 |
| Summary | This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Homozygous knockout mice for this gene exhibit eyelid defects. [provided by RefSeq, Aug 2016] |
Documents
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Resources
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| KN308333BN | Inhbb - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN308333LP | Inhbb - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN308333RB | Inhbb - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN508333 | Inhbb - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 657,00 EUR | |
| GA202166 | Inhbb CRISPRa kit - CRISPR gene activation of mouse inhibin beta-B | 1 657,00 EUR |