Gfpt1 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN306419RB

Gfpt1 - mouse gene knockout kit via CRISPR, HDR mediated



HDR-mediated knockout kit validation

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Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol Gfpt1
Locus ID 14583
Components

KN306419G1, Gfpt1 gRNA vector 1 in pCas-Guide CRISPR vector

KN306419G2, Gfpt1 gRNA vector 2 in pCas-Guide CRISPR vector

KN306419RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_013528
UniProt ID P47856
Synonyms 2810423A18Rik; AI324119; AI449986; GFA; GFAT; GFAT1; GFAT1m; Gfpt
Summary Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.[UniProtKB/Swiss-Prot Function]

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