Dll3 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN304621RB

Dll3 - mouse gene knockout kit via CRISPR, HDR mediated



HDR-mediated knockout kit validation

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Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol Dll3
Locus ID 13389
Components

KN304621G1, Dll3 gRNA vector 1 in pCas-Guide CRISPR vector

KN304621G2, Dll3 gRNA vector 2 in pCas-Guide CRISPR vector

KN304621RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_007866
UniProt ID O88516
Synonyms pu; pudgy
Summary Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.[UniProtKB/Swiss-Prot Function]

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