Cyba Mouse Gene Knockout Kit (CRISPR)

CAT#: KN304074LP

Cyba - mouse gene knockout kit via CRISPR, HDR mediated

Functional Cassette: GFP-puro Luciferase-Puro RFP-BSD mBFP-Neo



HDR-mediated knockout kit validation

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Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol Cyba
Locus ID 13057
Components

KN304074G1, Cyba gRNA vector 1 in pCas-Guide CRISPR vector

KN304074G2, Cyba gRNA vector 2 in pCas-Guide CRISPR vector

KN304074LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001301284, NM_007806
UniProt ID Q61462
Synonyms b558; nmf333; p22-phox; p22phox
Summary Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.[UniProtKB/Swiss-Prot Function]

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