Anti-CD44 CE/IVD for IHC - Hematopathology

Anti-CD44 CE/IVD for IHC - Hematopathology

 

Cluster of differentiation 44 (CD44) is a glycoprotein receptor for hyaluronic acid, which plays a fundamental role in cellular adhesion, stromal binding, migration, and cell-cell interactions. Studies have suggested that the CD44-hyaluronate interaction is central to tumor invasiveness. Positive staining with Anti-CD44 is implicated in a multitude of different cancer types, including breast, prostatic, renal cell, colonic, hepatocellular, and genitourinary carcinomas, as well as Non-Hodgkin's Lymphoma, metastatic melanoma, gastric cancer, and some soft tissue tumors. It has also been demonstrated that there is a positive correlation between tumor progression and increased expression of CD44v, a high molecular weight CD44 isoform that has been described in epithelial cells. Given the expression of CD44 in a wide range of cancers, the most practical application of CD44 immunostaining is its use in discriminating between urothelial transitional cell carcinoma in situ from non-neoplastic changes in the urothelium.

 

 

 

Breast Cancer section
Tonsil section

 

Search result : 6 product found

Refine your search :

RUOCE / IVD
  • Unconjugated 3
  • human 3
  • Primary antibody
  • mouse 6
  • IHC 6
  • IHC044 3
  • IHC144 3
APPLY FILTERS
REINITIALIZE


Cat#
Description
Cond.
Price Bef. VAT
IHC044-1
 1ml,Concentrated 
IHC044-100
 0.1ml,Concentrated 
IHC144-100
 0.1ml,Concentrated