NANOG Human Gene Knockout Kit (CRISPR)
CAT#: KN210243LP
NANOG - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
Product Images
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
| Donor DNA | Luciferase-Puro |
| Symbol | NANOG |
| Locus ID | 79923 |
| Components | KN210243G1, NANOG gRNA vector 1 in pCas-Guide CRISPR vector KN210243G2, NANOG gRNA vector 2 in pCas-Guide CRISPR vector KN210243LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001297698, NM_024865 |
| UniProt ID | Q9H9S0 |
| Summary | The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] |
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| KN210243 | NANOG - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN210243BN | NANOG - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN210243RB | NANOG - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN410243 | NANOG - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 657,00 EUR | |
| GA112732 | NANOG CRISPRa kit - CRISPR gene activation of human Nanog homeobox | 1 657,00 EUR |