FAM83B Human Gene Knockout Kit (CRISPR)

CAT#: KN210959LP

FAM83B - human gene knockout kit via CRISPR, HDR mediated



HDR-mediated knockout kit validation

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Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol FAM83B
Locus ID 222584
Components

KN210959G1, FAM83B gRNA vector 1 in pCas-Guide CRISPR vector

KN210959G2, FAM83B gRNA vector 2 in pCas-Guide CRISPR vector

KN210959LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001010872
UniProt ID Q5T0W9
Synonyms C6orf143
Summary Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.[UniProtKB/Swiss-Prot Function]

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