c-Myb (MYB) Human Gene Knockout Kit (CRISPR)
CAT#: KN209061RB
MYB - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
Product Images
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
| Donor DNA | RFP-BSD |
| Symbol | c-Myb |
| Locus ID | 4602 |
| Components | KN209061G1, c-Myb gRNA vector 1 in pCas-Guide CRISPR vector KN209061G2, c-Myb gRNA vector 2 in pCas-Guide CRISPR vector KN209061RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001130172, NM_001130173, NM_001161656, NM_001161657, NM_001161658, NM_001161659, NM_001161660, NM_005375, NR_134958, NR_134959, NR_134960, NR_134961, NR_134962, NR_134963, NR_134964, NR_134965 |
| UniProt ID | P10242 |
| Synonyms | c-myb; c-myb_CDS; Cmyb; efg |
| Summary | This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
Documents
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Resources
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| KN209061 | MYB - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN209061BN | MYB - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN209061LP | MYB - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN409061 | MYB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 657,00 EUR | |
| GA103048 | MYB CRISPRa kit - CRISPR gene activation of human MYB proto-oncogene, transcription factor | 1 657,00 EUR |