Specifications

Product Data
Format	1 x 96-well (pre-coated)
Assay Type	Solid Phase Sandwich ELISA
Assay Length	2h15min
Signal	Colorimetric
Curve Range	31.25-1000pg/ml
Sample Type	Serum, plasma, cell culture supernatant, buffered solutions and other body fluids.
Sample Volume	100 µl (50µl for serum/plasma)
Specificity	Recognizes both natural and recombinant human MCP-1
Sensitivity	5.8pg/ml
Components	ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
Background	This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013]
Gene Symbol	CCL2
Gene ID	6347
Standard Curve	Representative Standard Curve