Specifications

Product Data
Format	2 x 96-well (pre-coated)
Assay Type	Solid Phase Sandwich ELISA
Assay Length	3h45min
Signal	Colorimetric
Curve Range	31.25-1000 pg/ml
Sample Type	Serum, Plasma and other body fluids, Cell culture supernatants, Buffered solutions
Sample Volume	100 µl (50µl for serum/plasma)
Specificity	Recognizes both natural and recombinant human IL-31
Sensitivity	18 pg/ml
Cross Reactivity	No cross reactivity with IL-1b, IL-2, IL-4, IL-6, IL-6R, Gp130, IL-17F, IL-27, IL-33, GM-CSF
Components	ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
Background	IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START#Transcript exon combination :: AY499343.1, BC132998.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025094 [ECO:0000350] ##Evidence-Data-END##
Gene Symbol	IL31
Gene ID	386653
Standard Curve	Representative Standard Curve