Human IL-15 ELISA Kit, 2 x 96-well (pre-coated)

CAT#: EA101847

Human IL-15 ELISA Kit, 2 x 96-well (pre-coated)

Size: 1 x 48 wells (pre-coated) 1 x 96 wells (pre-coated) 2 x 96 wells (pre-coated)


Product Images

Specifications

Product Data
Format 2 x 96-well (pre-coated)
Assay Type Solid Phase Sandwich ELISA
Assay Length 3h45min
Signal Colorimetric
Curve Range 31.25-1000 pg/ml
Sample Type Serum, Plasma, Cell culture supernatant
Sample Volume 50 µl
Specificity Recognizes both natural and recombinant human IL-15
Sensitivity 18.3 pg/ml
Cross Reactivity No cross reaction with IL-2, IL-4, IL-7, IL-9, IL-10, IL-13, IL-21 and IFN-g
Components ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
Background The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
Gene Symbol IL15
Gene ID 3600
Standard Curve
Representative Standard Curve

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