Human IL-1 beta ELISA Set, 20 x 96-well
Product Images
Specifications
| Product Data | |
| Format | 20 x 96-well |
| Assay Type | Solid Phase Sandwich ELISA |
| Assay Length | From sample to end 3h45min |
| Signal | Colorimetric |
| Curve Range | 15.6-500 pg/ml |
| Sample Type | Serum, Plasma, Cell culture supernatant |
| Sample Volume | 100 µl |
| Specificity | Recognizes both natural (pro and mature) and recombinant human IL-1b |
| Sensitivity | 7 pg/ml |
| Cross Reactivity | No cross reactivity with other human cytokines |
| Components | ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition. |
| Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008] |
| Gene Symbol | IL1B |
| Gene ID | 3553 |
Documents
| SDS |