Human CD25 ELISA Set, 10 x 96-well

CAT#: EA101349

Human CD25 ELISA Set, 10 x 96-well


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Specifications

Product Data
Format 10 x 96-well
Assay Type Solid Phase Sandwich ELISA
Assay Length From sample to end 2h15min
Signal Colorimetric
Curve Range 68.75-2220 pg/ml
Sample Type Serum, Plasma, Cell culture supernatant
Sample Volume 100 µl
Specificity Recognizes both natural and recombinant human soluble IL-2R
Sensitivity 8 pg/ml
Cross Reactivity No cross reactivity with other human soluble receptors
Components ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
Background The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. [provided by RefSeq, Nov 2009]
Gene Symbol IL2RA
Gene ID 3559

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