Anti-c-Myc CE/IVD for IHC - Hematopathology

Anti-c-Myc CE/IVD for IHC - Hematopathology

 
The c-Myc gene is located at chromosome 8q24. It is required for progression through the cell cycle and promotes cellular proliferation. The t(8;14)(q24;q32) translocation and the c-Myc/immunoglobulin heavy-chain (IGH) fusion gene are not only in Burkitt lymphoma, but are also seen in diffuse large B-cell lymphoma, blastic mantle cell lymphoma and transformed follicular lymphoma. In another study on predicting c-Myc translocation in 17 cases of Burkitt lymphomas (BLs) and 19 cases of diffuse large B-cell lymphomas (DLBCLs), Ruzinova et al. reported that the sensitivity and specificity of this c-Myc antibody on identifying tumors harboring a c-Myc rearrangement reached 96% and 90% respectively. c-Myc antibody is a useful tool for identifying aggressive B-cell lymphomas likely to harbor a c-Myc rearrangement, and thus warrant genetic testing.
 
 
 
 
Breast carcinome section
Lung cancer section

 

Search result : 3 product found

Refine your search :

RUOCE / IVD
  • Unconjugated 3
  • human 3
  • Primary antibody
  • IHC 3
  • IHC448 3
APPLY FILTERS
REINITIALIZE


Cat#
Description
Cond.
Price Bef. VAT
IHC448-100
 0.1ml,Concentrated