Vigene Biosciences

 
Human miRNA

Human miRNA


MicroRNAs, also called miRNAs, are a class of RNAs characterized by their small size (on average 22 nucleotides - 21 to 24 in general). MiRNAs are single-stranded, non-coding and specific to eukaryotic cells. 
MiRNAs are post-transcriptional regulators capable of silencing the expression of a gene. Their pairing with a target message RNA (mRNA) can lead to the inhibition of its translation or to its degradation depending on the degree of complementarity between the miRNA sequence and that of its target mRNA. MiRNAs are thus part of the regulatory pathways for gene expression.
MiRNAs are also capable of directly methylating DNA in order to turn off genes.
To date, more than 2500 mature miRNAs have been discovered in humans, targeting more than 50% of the genome. A single gene can be regulated by several miRNAs and conversely a single miRNA can regulate several genes due to the often partial complementarity. 

Cat#
Description
Size
Price Excl. VAT
CR200772
 500µL 
CR214660
 500µL 
CR225197
 500µL 
CR241635
 500µL 
CR263097
 500µL 
VR201824
 100µl 
VR214947
 100µl 
VR225893
 100µl 
VR243237
 100µl 
VR264009
 100µl 
VR278254
 100µl 
CR200812
 500µL 
CR214674
 500µL 
CR225221
 500µL 
CR241835
 500µL 
CR277436
 500µL 
CR291977
 500µL 
VR225910
 100µl 
VR243607
 100µl 
VR264010
 100µl 
VR292526
 100µl 
CR200931
 500µL 
CR214704
 500µL 
CR202912
 500µL 
CR225227
 500µL 
CR241836
 500µL 
CR263193
 500µL 
VR201923
 100µl 
VR215037
 100µl 
VR204497
 100µl 
VR225922
 100µl 
VR243238
 100µl 
VR264526
 100µl 
VR278305
 100µl 
CR201162
 500µL 
CR214764
 500µL 
CR254197
 500µL 
CR242181
 500µL 
CR263258
 500µL 
CR277580
 500µL 
CR292101
 500µL 
VR201951
 100µl 
VR226027
 100µl 
VR264632
 100µl 
VR278469
 100µl 
VR292719
 100µl 
CR201238
 500µL 
CR214828
 500µL 
CR203139
 500µL 
CR254299
 500µL 
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