Human Carbohydrate sulfotransferase 4 (CHST4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CHST4
Locus ID	10164
Kit Components	GA106904G1, Carbohydrate sulfotransferase 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106904G2, Carbohydrate sulfotransferase 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106904G3, Carbohydrate sulfotransferase 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001166395, NM_005769
UniProt ID	Q8NCG5
Synonyms	GlcNAc6ST2; GST3; HECGLCNAC6ST; LSST
Summary	This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded enzyme transfers sulfate from 3'phosphoadenosine 5'phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]