Human Aspartate Aminotransferase (GOT1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GOT1
Locus ID	2805
Kit Components	GA101875G1, Aspartate Aminotransferase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101875G2, Aspartate Aminotransferase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101875G3, Aspartate Aminotransferase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_002079
UniProt ID	P17174
Synonyms	ASTQTL1; cAspAT; cCAT; GIG18
Summary	Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. [provided by RefSeq, Jul 2008]