Cd8a Rat Monoclonal Antibody [Clone ID: KT15]

CAT#: SM011APC

Cd8a rat monoclonal antibody, clone KT15, APC


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Specifications

Product Data
Clone Name KT15
Applications FC
Recommended Dilution Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc recepto
Reactivities Mouse
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen T cell clone, C6. Spleen cells from a Spraque Dawley rat immunised with the C6 T cell clone were fused with cells of the NSO mouse myeloma cell line.
Specificity Mouse Ly2.1 and Ly2.2 cells. This antibody reacts with the CD8 alpha chain (non polymorphic).
Formulation PBS containing 0.09% Sodium Azide, 5% Sucrose and 1% Bovine Serum Albumin
Label: APC
State: Lyophilized purified IgG
Label: Allophycocyanin
Reconstitution Method Restore with 1 ml distilled water
Conjugation APC
Storage Prior to and following reconstitution store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name Mus musculus CD8 antigen, alpha chain (Cd8a), transcript variant 1
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data

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