BIOMIMESYS® liver - hydroscaffold 3D in black 96-well plate

Cat# BIO_LIV_96_24_B10

Size : 10plates/24wellsfilled

Brand : Biomimesys

Contact local distributor :


Phone : +1 850 650 7790

BIOMIMESYS® is a unique groundbreaking 3D cell culture technology which associates the behavior of a solid scaffold and of a hydrogel. It provides a cell culture microenvironment reproducing all aspects of human tissues, including matrix architecture, cellular organization, cell-cell and cell-matrix interactions.

BIOMIMESYS® Liver
BIOMIMESYS® Liver

Depending on the organ, extracellular matrix components and their proportions may vary, allowing a more or less dense and compact cellular environment (different Elastic Moduli, porosities). 

BIOMIMESYS® matrices are made of Hyaluronic Acid (HA), the main glycosaminoglycan (GAG) of the ECM, collagens and adhesion proteins. Our patented manufacturing process allows to preserve the natural properties of HA and therefore synthesizing proprietary Hydroscaffold™.

Tuning the composition of BIOMIMESYS® matrix allows to mimic the cellular microenvironment of any organ or tissue of interest.

BIOMIMESYS® Liver

HA + RGDS
Galactosamine
Collagen I
Collagen IV

Elastic Modulus: 0.6 kPa

Cells already tested

Primary human cells: Primary hepatocytes

Cell lines:

  • Hepatocytes : HepG2/HepaRG
  • Stellate: LX2

iPSC-derived human liver organoids or hepatocytes

Technical documents

  • BIOMIMESYS® Liver – Brochure
  • BIOMIMESYS® Liver – Example of CoA (Certificate Of Analysis)
  • BIOMIMESYS® Liver – Technical Data Sheet (TDS)
  • BIOMIMESYS® Liver – Material Safety Data Sheet (MSDS)

For a better cell longevity and a proper phenotype

BIOMIMESYS® Liver is dedicated to the culture of liver cells such as hepatocytes. Unlike in 2D culture, primary human hepatocytes in 3D within BIOMIMESYS® Liver had their enzymatic activities (e.g. CYPs) and albumin secretion maintained until 21 days.

For a better in vitro/in vivo correlation

By using a liver-specific ECM with BIOMIMESYS® Liver, steatotic effect on HepaRG cell line is closer to clinical observations.

BIOMIMESYS® is compatible with all downstream analytical technologies.

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