Pdcd1lg2 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN312993BN
Pdcd1lg2 - mouse gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro Luciferase-Puro RFP-BSD
HDR-mediated knockout kit validation
Product Images
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
| Donor DNA | mBFP-Neo |
| Symbol | Pdcd1lg2 |
| Locus ID | 58205 |
| Components | KN312993G1, Pdcd1lg2 gRNA vector 1 in pCas-Guide CRISPR vector KN312993G2, Pdcd1lg2 gRNA vector 2 in pCas-Guide CRISPR vector KN312993BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_021396 |
| UniProt ID | Q9WUL5 |
| Synonyms | B7-DC; Btdc; F730015O22Rik; PD-L2 |
| Summary | Involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| KN312993 | Pdcd1lg2 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN312993LP | Pdcd1lg2 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN312993RB | Pdcd1lg2 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN512993 | Pdcd1lg2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 657,00 EUR | |
| GA206263 | Pdcd1lg2 CRISPRa kit - CRISPR gene activation of mouse programmed cell death 1 ligand 2 | 1 657,00 EUR |