IRS-1(Ser307) Polyclonal Antibody, Biotin Conjugated
Cat# bs-2736R-Biotin
Size : 100ul
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IRS-1(Ser307) Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-2736R-Biotin |
| Product Name | IRS-1(Ser307) Polyclonal Antibody, Biotin Conjugated |
| Applications | ELISA, IHC-P, IHC-F |
| Specificity | This phosphorylation site is homologous to Ser302 in Mouse and Rat. |
| Reactivity | Human, Mouse, Rat, Goat |
| Predicted Reactivity | Dog, Cow, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human IRS1 around the phosphorylation site of Ser307 [TE(p-S)IT] |
| Modification Site | Ser307 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 3667 |
| Swiss Prot | P35568 |
| Subcellular location | Cell membrane |
| Synonyms | HIRS-1; Insulin receptor substrate 1; IRS-1; IRS1 |
| Background | May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). |
| Application Dilution | |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |