HNF4A Antibody - middle region : Biotin
Cat# ARP32632_P050-Biotin
Size : 100ul
Brand : Aviva Systems Biology
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Phone : +1 850 650 7790
HNF4A Antibody - middle region : Biotin (ARP32632_P050-Biotin)
| Datasheets/Manuals | Printable datasheet for anti-HNF4A (ARP32632_P050-Biotin) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | Biotin |
| Application | IHC, WB |
| Additional Information | IHC Information: Small intestine IHC Information: Liver |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human HNF4A |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%; Sheep: 93%; Zebrafish: 90% |
| Peptide Sequence | Synthetic peptide located within the following region: RGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEV |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-HNF4A (ARP32632_P050-Biotin) antibody is Catalog # AAP32632 (Previous Catalog # AAPP03642) |
| Sample Type Confirmation | HNF4A is strongly supported by BioGPS gene expression data to be expressed in OVCAR3 |
| Reference | Holmkvist,J., (2008) Diabetes 57 (6), 1738-1744 |
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| Gene Symbol | HNF4A |
| Gene Full Name | Hepatocyte nuclear factor 4, alpha |
| Alias Symbols | TCF, HNF4, MODY, FRTS4, MODY1, NR2A1, TCF14, HNF4a7, HNF4a8, HNF4a9, NR2A21, HNF4alpha |
| NCBI Gene Id | 3172 |
| Protein Name | Hepatocyte nuclear factor 4-alpha |
| Description of Target | The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression |
| Uniprot ID | P41235-5 |
| Protein Accession # | NP_787110 |
| Nucleotide Accession # | NM_175914 |
| Protein Size (# AA) | 452 |
| Molecular Weight | 50kDa |
| Protein Interactions | PIAS4; SUMO1; SUMO2; RNF4; SUB1; CREBBP; TBP; TAF9; TAF6; TADA2A; GTF2H1; GTF2B; ANP32B; MDM2; GPS2; PPARGC1A; HNF4A; NCOA6; SMAD4; SMAD3; PNRC2; COPS5; PNRC1; NR0B2; NRIP1; UBE2I; PROX1; NPPA; SREBF2; VDR; MAPK3; MAPK1; SIRT1; SREBF1; XPO1; SP1; HDAC3; T |
