Application
| IHC-P, IHC-Fr |
---|---|
Primary Accession | P28906 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Clone Names | EP88 |
Calculated MW | 41kDa |
Dilution | IHC-Fr (1:50-1:200), IHC-P (1:100), |
Gene ID | 947 |
---|---|
Other Names | Hematopoietic progenitor cell antigen CD34, CD34, CD34 |
Reconstitution & Storage | Store at 2-8°C |
Precautions | CD34 Antibody (clone EP88) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD34 |
---|---|
Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues |