DEPC [1609-47-8]
Katalog-Nummer NB-64-35112-100mg
Size : 100mg
Marke : Neo Biotech
Contact local distributor :
Telefonnummer : +1 850 650 7790
DEPC
Alias Diethyl pyrocarbonate
DEPC (Diethyl pyrocarbonate) is a potent and irreversible RNase inhibitor containing histidine residues.DEPC can be used to prevent RNA enzyme degradation by modifying histidine residues with carboxylation resulting in enzyme inactivation. DEPC showed inhibitory effect on the central chemical sensitivity of rabbits. DEPC modified His, Tyr, Ser and Thr residues.
Product Introduction
Bioactivity
Chemical Properties
| Description | DEPC (Diethyl pyrocarbonate) is a potent and irreversible RNase inhibitor containing histidine residues.DEPC can be used to prevent RNA enzyme degradation by modifying histidine residues with carboxylation resulting in enzyme inactivation. DEPC showed inhibitory effect on the central chemical sensitivity of rabbits. DEPC modified His, Tyr, Ser and Thr residues. |
| In vivo | Insulin binding to rat liver plasma membranes is inhibited in a time- and dose-dependent fashion by prior treatment of membranes with the histidine-specific reagent diethyl pyrocarbonate.[1] |
| Synonyms | Diethyl pyrocarbonate |
| Molecular Weight | 162.14 |
| Formula | C6H10O5 |
| Cas No. | 1609-47-8 |
| Smiles | CCOC(=O)OC(=O)OCC |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (339.21 mM), Sonication is recommended.  H2O: 30 mg/mL (185.03 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
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