Human Calcium binding protein P22 (CHP1) activation kit by CRISPRa

CAT#: GA107760

CHP1 CRISPRa kit - CRISPR gene activation of human calcineurin like EF-hand protein 1



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CHP1
Locus ID 11261
Kit Components

GA107760G1, Calcium binding protein P22 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107760G2, Calcium binding protein P22 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107760G3, Calcium binding protein P22 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_007236
UniProt ID Q99653
Synonyms CHP; p22; p24; Sid470p; SLC9A1BP
Summary This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity. [provided by RefSeq, Jul 2008]

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