Antibody Design Labs

Founded in 2011, Antibody Design Labs is committed to become a leader in the field of recombinant antibody technologies. Over the last 30 years, techniques have rapidly evolved to make antibodies a primary component of modern research, modern diagnostic, and emerging therapeutics.  Following the initial discovery of monoclonal hybridomas, technologies such as phage display have become routine in many laboratories.  Still, getting the right antibody for the right application can be a long journey where high-throughput approaches can be very effective but at prohibitive costs.  Antibody Design Labs will be a centralized place to access tools, information, techniques in the field of recombinant antibody generation, engineering and design.

Antibody Design Labs is offering a wide choice of phage & phagemid vectors to overcome the challenge of phage display. Selection of binders is a complex process depending on multiple variables and experimental conditions, making time and resources the main limiting factors for successful biopannings. We currently offer varied options for display on the N-terminal side of the full-length gene III protein with the PelB leader peptide either using a phagemid system or phage vectors. The phagemids are best suited for the display of antibodies such as scFv and Fab fragments but can also be used to display peptides at a low valency; phage vectors produce a multivalent display and are best suited for peptides and scFv. This short guide will help you with the choice of the vector that best suits your project.
  • Multiple tags and cloning sites.
  • Varied display strategies.
  • No background expression to maintain library integrity & stability.
  • Inducible expression & display.
Competent cells

Competent cells

Cellular competence refers to a cell's ability to absorb foreign (extracellular) DNA from its environment. The process of genetic absorption is called transformation. In some cases, the genetic material absorbed by a cell may be incorporated, or recombined, into its own genome. This incorporation of genetic material into the host genome is called horizontal gene transfer (HGT) or lateral gene transfer.
Natural competence and gene transfer have facilitated many adaptations in prokaryotic and eukaryotic cells. Competent cells can either occur naturally or be made competent artificially.
There are two types of artificially competent cells: chemically competent cells and electro-competent cells. Chemically competent cells are cells that have been made competent by a salt treatment followed by a heat shock step. Electro-competent cells are made competent by using an electrical impulse from an electroporator to create temporary pores (poration) in the cell membrane of prokaryotic or eukaryotic cells.

H. T. Preis
 10 x 500 ul 
 10 x 500 ul