Human Prostatic Acid Phosphatase (ACPP) activation kit by CRISPRa

CAT#: GA100043

ACPP CRISPRa kit - CRISPR gene activation of human acid phosphatase, prostate



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ACP3
Locus ID 55
Kit Components

GA100043G1, Prostatic Acid Phosphatase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100043G2, Prostatic Acid Phosphatase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100043G3, Prostatic Acid Phosphatase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001099, NM_001134194, NM_001292037
UniProt ID P15309
Synonyms 5 -NT; 5'-NT; ACP-3; ACP3
Summary This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]

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