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Mouse Monoclonal Anti-HPV-16 (Human Papilloma Virus 16) [Clone SPM257]
Katalog-Nummer NB-36-01111-P0
Size : 20ug
Marke : Neo Biotech
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Telefonnummer : +1 850 650 7790
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Printable Datasheet
HPV-16 (Human Papilloma Virus 16) Antibody [SPM257]
Catalog Number Formulation Size Price
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day
Formalin-fixed, paraffin-embedded human Cervix stained with HPV-16 Monoclonal Antibody (SPM257)
Applications & Dilutions
Applications Tested Dillution Protocol Note
Immunofluorescence (IF)
1-3ug/ml
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Summary
Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.
Product Properties & Targets
Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunofluorescence, Immunohistochemistry
Species Reactivity
HPV-16
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
N/A
Gene Name
N/A
Positive Control
HPV-16 infected cells. Cervical tissue.
Immunogen
Human papilloma virus type 16, major capsid protein L1
Alternate Names
N/A, N/A, HPV-16; HPV-16 capsid; HPV16 L1; HPV16 major capsid protein L1; Human papillomavirus type 16 L1; Human papillomavirus type 16 major capsid protein L1
Functions
- N/A
Key References
- McLean CS, J Clin Pathol, 1990; 43:488-492.
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.
Supplied as
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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