General Info
| Host: | Mouse |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-Low affinity immunoglobulin epsilon Fc receptor is suitable for use in Western Blot research applications. |
| Clonality: | Monoclonal |
| Clone ID: | 10H2 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | FCER2 |
| Gene ID: | 2208 |
| Uniprot ID: | FCER2_HUMAN |
| Specificity: | The antibody detects endogenous CD23 proteins. |
| Immunogen: | Synthetic Peptide of CD23 |
Description
| Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. |
| Protein Name | Low Affinity Immunoglobulin Epsilon Fc ReceptorBlast-2C-Type Lectin Domain Family 4 Member JFc-Epsilon-RiiImmunoglobulin E-Binding FactorLymphocyte Ige ReceptorCd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form |
| Database Links | Reactome: R-HSA-2197563Reactome: R-HSA-6783783Reactome: R-HSA-6785807 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinLipid-AnchorSecretedAlso Exists As A Soluble Excreted FormScd23 |
| Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibodyAnti-Blast-2 antibodyAnti-C-Type Lectin Domain Family 4 Member J antibodyAnti-Fc-Epsilon-Rii antibodyAnti-Immunoglobulin E-Binding Factor antibodyAnti-Lymphocyte Ige Receptor antibodyAnti-Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form antibodyAnti-FCER2 antibodyAnti-CD23A antibodyAnti-CLEC4J antibodyAnti-FCE2 antibodyAnti-IGEBF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance