Human Proteinase Activated Receptor 4 (F2RL3) activation kit by CRISPRa

CAT#: GA105987

F2RL3 CRISPRa kit - CRISPR gene activation of human F2R like thrombin or trypsin receptor 3



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol F2RL3
Locus ID 9002
Kit Components

GA105987G1, Proteinase Activated Receptor 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105987G2, Proteinase Activated Receptor 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105987G3, Proteinase Activated Receptor 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_003950
UniProt ID Q96RI0
Synonyms PAR4
Summary This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016]

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