Human Proteinase Activated Receptor 3 (F2RL2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	F2RL2
Locus ID	2151
Kit Components	GA101498G1, Proteinase Activated Receptor 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101498G2, Proteinase Activated Receptor 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101498G3, Proteinase Activated Receptor 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256566, NM_004101
UniProt ID	O00254
Synonyms	PAR-3; PAR3
Summary	This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]