Description
Fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (caspase-like) activity of the proteasome which may be stimulated in the presence of Mg2+ ions and rapidly inactivated by N-acetylimidazole.
Size : 5mg
Lyophilized. Off white powder
348086-66-8
VD-OEIA-0158
C35H44N4O9
664.75
>=95%
DMSO
-20°C
Z-Leu-Leu-Glu-7-amido-4-methylcoumarin
50mg, 5mg
Fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (caspase-like) activity of the proteasome which may be stimulated in the presence of Mg2+ ions and rapidly inactivated by N-acetylimidazole.
1.M. Orlowski et al.; Biochemistry 30, 5999 (1991).
2.B. Yu et al.; J. Biol. Chem. 266, 17396 (1991).
3.M.E. Pereira et al.; Arch. Biochem. Biophys. 294, 1 (1992).
4.S. Tsubuki et al.; Biochem. Biophys. Res. Commun. 196, 1195 (1993).