keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VTP-27999 TFA [1013937-63-7]
Katalog-Nummer T7668-50mg
Size : 50mg
Marke : TargetMol
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VTP-27999 TFA
Catalog No. T7668 CAS 1013937-63-7
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
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VTP-27999 TFA, CAS 1013937-63-7
| Description | VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM). |
| Targets&IC50 | Renin:0.47 nM |
| In vitro | In vitro,VTP-27999 increased renin immunoreactivity for a given amount of renin by ≥ 30%[]1 |
| Molecular Weight | 639.1 |
| Formula | C28H42ClF3N4O7 |
| CAS No. | 1013937-63-7 |
Storage
Solubility Information
H2O: 10 mg/mL (15.65 mM), Sonication is recommended.
References and Literature
1. Krop M , Lu X , Verdonk K , et al. New Renin Inhibitor VTP-27999 Alters Renin Immunoreactivity and Does Not Unfold Prorenin[J]. Hypertension, 2013, 61(5):1075-1082. 2. Ishchenko A , Liu Z , Lindblom P , et al. Structure-Based Design Technology Contour and Its Application to the Design of Renin Inhibitors[J]. Journal of Chemical Information and Modeling, 2012, 52(8):2089-2097.