THY1 Antibody

Katalog-Nummer OAEE01007

Size : 100tests(T100)

Marke : Aviva Systems Biology

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THY1 Antibody

Datasheets/ManualsPrintable datasheet for THY1 Antibody
Product Info
Predicted Species ReactivityDog|Horse|Human|Non-human Primate|Porcine
Product FormatStabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
ClonalityMonoclonal
Clone5E10
IsotypeIgG1
HostMouse
ConjugationFITC
ApplicationFC
Reconstitution and Storage2°C to 8°C
ImmunogenHEL erythroleukemia cells
PurificationPurified by size-exclusion chromatography
Concentration4 ul / test
SpecificityThe mouse monoclonal antibody 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
ReferenceHoppstadter J, Diesel B, Zarbock R, Breinig T, Monz D, Koch M, Meyerhans A, Gortner L, Lehr CM, Huwer H, Kiemer AK: Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages. Respir Res. 2010 Sep 15;11:124.
Kroeze KL, Jurgens WJ, Doulabi BZ, van Milligen FJ, Scheper RJ, Gibbs S: Chemokine-mediated migration of skin-derived stem cells: predominant role for CCL5/RANTES. J Invest Dermatol. 2009 Jun;129(6):1569-81.
Carlsten M, Bjorkstrom NK, Norell H, Bryceson Y, van Hall T, Baumann BC, Hanson M, Schedvins K, Kiessling R, Ljunggren HG, Malmberg KJ: DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells. Cancer Res. 2007 Feb 1;67(3):1317-25.
Chin-Yee IH, Keeney M, Stewart AK, Belch A, Bence-Buckler I, Couban S, Howson-Jan K, Rubinger M, Stewart D, Sutherland R, Paragamian V, Bhatia M, Foley R: Optimising parameters for peripheral blood leukapheresis after r-metHuG-CSF (filgrastim) and r-metHuSCF (ancestim) in patients with multiple myeloma: a temporal analysis of CD34(+) absolute counts and subsets. Bone Marrow Transplant. 2002 Dec;30(12):851-60.
St Louis DC, Woodcock JB, Franzoso G, Blair PJ, Carlson LM, Murillo M, Wells MR, Williams AJ, Smoot DS, Kaushal S, Grimes JL, Harlan DM, Chute JP, June CH, Siebenlist U, Lee KP: Evidence for distinct intracellular signaling pathways in CD34+ progenitor to dendritic cell differentiation from a human cell line model. J Immunol. 1999 Mar 15;162(6):3237-48.
Ito T, Inaba M, Inaba K, Toki J, Sogo S, Iguchi T, Adachi Y, Yamaguchi K, Amakawa R, Valladeau J, Saeland S, Fukuhara S, Ikehara S: A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells. J Immunol. 1999 Aug 1;163(3):1409-19.And many other.
Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells. Blood. 2001 May 1;97(9):2741-9.
Gene SymbolTHY1
Gene Full NameThy-1 cell surface antigen
Alias SymbolsCD90, CDw90, thy-1 antigen, thy-1 membrane glycoprotein, Thy-1 T-cell antigen.
NCBI Gene Id7070
Protein NameThy-1 membrane glycoprotein
Description of TargetMay play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Uniprot IDP04216
Protein Accession #NP_006279.2
Nucleotide Accession #NM_006288.3