Tcp1 Antibody
Katalog-Nummer OAED00063
Size : 50ug
Marke : Aviva Systems Biology
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Tcp1 Antibody (OAED00063)
| Datasheets/Manuals | Printable datasheet for Tcp1 Antibody (OAED00063) |
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| Predicted Species Reactivity | Chicken|Dog|Hamster|Human|Mouse|Plant|Rabbit|Rat|Sheep |
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| Clonality | Monoclonal |
| Clone | 23c |
| Isotype | IgG2c |
| Host | Rat |
| Application | Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot |
| Reconstitution and Storage | Long Term Storage : -20C |
| Immunogen | Recombinant mouse TCP-1alpha (C-terminal fragment). |
| Specificity | Recognizes human, mouse, rat, chicken, dog, hamster, plant, rabbit and sheep TCP-1alpha. Detects a band of ~60kDa by Western blot. |
| Formulation | Liquid. In PBS containing 50% glycerol and 0.09% sodium azide. |
| Purity | Protein G affinity purified. |
| Application Info | Immunocytochemistry Immunohistochemistry Immunoprecipitation Western Blot (1:1000, colorimetric) Optimal conditions must be determined individually for each application. |
| Reference | Association of Simian Virus 40 Vp1 with 70-Kilodalton Heat ShockProteins and Viral Tumor Antigens: H. Kasamatsu, et al. ; J. Virol. 83, 37 (2008), Application(s): WB, IP using monkey cell lysates, Abstract; Identification of a host protein essential for assembly of immature HIV-1 capsids: J.R. Lingappa, et al. ; Nature 415, 88 (2002), Application(s): IP using plant (wheat) samples, Abstract; The interaction of the chaperonin tailless complex polypeptide 1 (TCP1) ring complex (TRiC) with ribosome-bound nascent chains examined using photo-cross-linking: J. Frydman, et al. ; J. Cell Biol. 149, 591 (2000), Application(s): IP using rabbit samples, Abstract; A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins: K.R. Willison, et al. ; EMBO J. 12, 2847 (1993), Application(s): WB, ICC using human, mouse, rat, & chicken samples, Abstract; T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol: K. Willison, et al. ; Nature 358, 249 (1992), Application(s): ICC using human samples, Abstract; |
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| Gene Symbol | Tcp1 |
| Gene Full Name | t-complex protein 1 |
| Alias Symbols | AI528772;c-c;c-cpn;CCT;Cct1;Ccta;CCT-alpha;p6;p63;tailless complex polypeptide 1A;tailless complex polypeptide 1B;t-complex polypeptide 1;T-complex protein 1 subunit alpha;T-complex protein 1 subunit alpha A;T-complex protein 1 subunit alpha B;Tcp-;Tcp-1;TCP-1-A;TCP-1-alpha;TCP-1-B;Tp6;Tp63;TR;TRic. |
| NCBI Gene Id | 21454 |
| Protein Name | T-complex protein 1 subunit alpha |
| Description of Target | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity). |
| Uniprot ID | P11983 |
| Protein Accession # | NP_001277641.1; NP_038714.2 |
| Nucleotide Accession # | NM_001290712.1; NM_013686.4 |
