Stemolecule™ ec23
SRP002 / SRP002-2
Brand: Stemolecule
A light-stable pan-RAR receptor agonist that maintains the same biological activity as ATRA (all-trans retinoic acid).
CAS Number: 104561-41-3
Alternate Name(s):
- 4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylethynyl) benzoic acid
Note: shown do not include shipping and handling charges.
Product Information
Human TERA2.cl.SP12 EC cells exposed to either ec23 or ATRA form populations of terminally differentiated neurons after 21 days. Immunocytochemical staining for neurofilament-200 was performed on differentiated cultures.
SR-P002 and SR-P002-2 SDS
Christie VB; Barnard JH; Batsanov AS; Bridgens CE; Cartmell EB; Collings JC; Maltman DJ; Redfern CPF; Marder TB; Przyborski S; Whiting A. Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation. Org Biomol Chem 6: 3497 (2008).
Additional Publications
- Goncalves KE; Phillips S; Shah DSH; Athey D; Przyborski S. Application of biomimetic surfaces and 3D culture technology to study the role of extracellular matrix interactions in neurite outgrowth and inhibition. Biomaterials Advances 144:213204 (2022).
- Tan SM; Altschuler G; Zhao TY; Ang HS; Yang H; Lim B; Vardy L; Hide W; Thomson AM; Lareu RR. Divergent LIN28-mRNA associations result in translational suppression upon the initiation of differentiation. Nucl Acids Res 42: 7997 (2014).
- Clemens G; Flower KR; Henderson AP; Whiting A; Przyborski SA; Jimenez-Hernandez M; Ball F; Basssan P; Cinque G; Gardner P. The action of all-trans-retinoic acid (ATRA) and synthetic retinoid analogues (EC19 and EC23) on human pluripotent stem cells differentiation investigated using single cell infrared microspectroscopy. Mol Biol Syst 9: 699 (2013).