SLC2A4 Antibody - N-terminal region : HRP

Katalog-Nummer ARP43785_P050-HRP

Size : 100ul

Marke : Aviva Systems Biology

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SLC2A4 Antibody - N-terminal region : HRP (ARP43785_P050-HRP)

Datasheets/ManualsPrintable datasheet for anti-SLC2A4 (ARP43785_P050-HRP) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human SLC2A4
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Peptide SequenceSynthetic peptide located within the following region: LQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALSV
Concentration0.5 mg/ml
Blocking PeptideFor anti-SLC2A4 (ARP43785_P050-HRP) antibody is Catalog # AAP43785 (Previous Catalog # AAPP25374)
ReferenceMcGee,S.L., (2008) Diabetes 57 (4), 860-867
Gene SymbolSLC2A4
Gene Full NameSolute carrier family 2 (facilitated glucose transporter), member 4
Alias SymbolsGLUT4
NCBI Gene Id6517
Protein NameSolute carrier family 2, facilitated glucose transporter member 4
Description of TargetSLC2A4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus.This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP14672
Protein Accession #NP_001033
Nucleotide Accession #NM_001042
Protein Size (# AA)509
Molecular Weight55kDa
Protein InteractionsUBC; FAR1; P3H1; FKBP10; ESYT2; GNL3L; CRNKL1; STRN3; ARFIP1; SDF2L1; P3H4; KLHL41; PDIA6; MVP; RAB7A; UBE2N; PSMD7; PRKAR1A; NSF; IDH1; HSP90AA1; HK2; GAPDH; DLD; CTSD; SERPINH1; BSG; ARF5; ARF3; ACTN1; ACTN4; ACOX1; DSK2; UBI4; C1QTNF5; MAP1S; EHD2; UBE