Pyridostatin Trifluoroacetate Salt
Katalog-Nummer 463276-5mg
Size : 5mg
Marke : US Biological
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Grade
Highly PurifiedShipping Temp
RTStorage Temp
-20°C4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(2,2,2-trifluoroacetate); Pyridostatin TFA Salt
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB). Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets gene bodies containing clusters of sequences with a propensity for G-quadruplex formation. As a result, pyridostatin modulated the expression of these genes, including the proto-oncogene SRC.
Synonyms:
4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(2,2,2-trifluoroacetate); Pyridostatin TFA Salt
CAS No:
1472611-44-1
Free Base: 1085412-37-8
Free Base: 1085412-37-8
Molecular Formula:
C37H35F9N8O11
Molecular Weight:
938.72
Purity:
≥95%
Appearance:
White to off-white solid
Solubility:
Soluble in DMSO, not soluble in water
Storage and Stability:
Store at -20°C. Stable for 6 months after receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.