PLEKHM2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommended Dilution	WB: 0.5 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivities	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	PLEKHM2 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human PLEKHM2.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Affinity chromatography purified via peptide column
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Gene Name	pleckstrin homology and RUN domain containing M2
Database Link	NP_055979 Entrez Gene 69582 MouseEntrez Gene 313667 RatEntrez Gene 23207 Human UniProt ID Q8IWE5
Background	PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
Synonyms	SKIP
Reference Data
Protein Families	Druggable Genome