PCBD1 Antibody - N-terminal region : FITC
Katalog-Nummer ARP32447_P050-FITC
Size : 100ul
Marke : Aviva Systems Biology
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Telefonnummer : +1 850 650 7790
PCBD1 Antibody - N-terminal region : FITC (ARP32447_P050-FITC)
| Datasheets/Manuals | Printable datasheet for anti-PCBD1 (ARP32447_P050-FITC) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | FITC: Fluorescein Isothiocyanate |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human PCBD1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFM |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-PCBD1 (ARP32447_P050-FITC) antibody is Catalog # AAP32447 (Previous Catalog # AAPP03443) |
| Reference | Hevel,J.M., (2006) Mol. Genet. Metab. 88 (1), 38-46 |
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| Gene Symbol | PCBD1 |
| Gene Full Name | Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| Alias Symbols | PCD, PHS, DCOH, PCBD |
| NCBI Gene Id | 5092 |
| Protein Name | Pterin-4-alpha-carbinolamine dehydratase |
| Description of Target | PCBD1 is pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).This gene encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Uniprot ID | P61457 |
| Protein Accession # | NP_000272 |
| Nucleotide Accession # | NM_000281 |
| Protein Size (# AA) | 104 |
| Molecular Weight | 12kDa |
| Protein Interactions | TFF3; PCBD1; LNX1; FXR2; ACIN1; RPS24; APP; CDK5RAP2; UBC; HNF1A; DCUN1D1; COPS5; CUL1; CUL3; CUL4A; CUL4B; CUL5; MYC; ZNF567; ZNF714; TRIM5; PCBD2; EHMT1; SOWAHC; PAPOLG; HES4; CALCOCO1; MIS18BP1; KLF13; BRD7; ZNF451; DIP2C; SCMH1; POLR3A; WWP1; DENND4A; |
