Ovine CXCL10 (IP-10) ELISA
Katalog-Nummer DIY0893V-003
Size : 1Set
Marke : Kingfisher Biotech
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Telefonnummer : +1 850 650 7790
Ovine CXCL10 ELISA Data
Ovine CXCL10 ELISA Kit Components
| Component | Usage | Quantity | Catalog # |
| Anti-Bovine CXCL10 (IP-10) Polyclonal Antibody | Capture Antibody | 100 µg | PB0385B-100 |
| Biotinylated Anti-Bovine CXCL10 (IP-10) Polyclonal Antibody | Detection Antibody | 50 µg | PBB0393B-050 |
| Ovine CXCL10 (IP-10) recombinant Protein | Standard | 5 µg | RP0490V-005 |
Ovine CXCL10 ELISA Specifications
The Ovine CXCL10 (IP-10) Do-It-Yourself ELISA contains capture antibody, protein standard, and detection antibody for development of a Ovine CXCL10 (IP-10) ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. A working knowledge of ELISA is strongly recommended. The quantities of components provided are not matched. Components may also be purchased separately.
For additional tips and techniques to ensure a successful ELISA, check out our ELISA Technical Guide.
CXCL10 Background
C-X-C motif chemokine 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is a member of the C-X-C chemokine family. CXCL10 (IP-10) is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL10 (IP-10) elicits its effects by binding to the cell surface chemokine receptor CXCR3.
Alternate Names - CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10